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Pierce, okay. L., Premont, R. T. & Lefkowitz, R. J. Seven-transmembrane receptors. Nature Rev. Mol. telephone Biol. 3, 639–650 (2002).
Neves, S. R., Ram, P. T. & Iyengar, R. G protein pathways. Science 296, 1636–1639 (2002).
Rozengurt, E., Guha, S. & Sinnett-Smith, J. Gastrointestinal peptide signalling in fitness and sickness. Eur. J. Surg. Suppl. 23–38 (2002).
Mills, G. B. & Moolenaar, W. H. The rising role of lysophosphatidic acid in melanoma. Nature Rev. cancer three, 582–591 (2003).
Gutkind, J. S. mobilephone increase manage with the aid of G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17, 1331–1342 (1998).
Marinissen, M. J. & Gutkind, J. S. G-protein-coupled receptors and signaling networks: emerging paradigms. developments Pharmacol. Sci. 22, 368–376 (2001).
young, D., Waitches, G., Birchmeier, C., Fasano, O. & Wigler, M. Isolation and characterization of a brand new cellular oncogene encoding a protein with dissimilar skills transmembrane domains. cell forty five, 711–719 (1986). This groundbreaking work turned into the primary study to establish a gene that encodes a seven transmembrane receptor, named MAS , as an oncogene.
Julius, D., Livelli, T. J., Jessell, T. M. & Axel, R. Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation. Science 244, 1057–1062 (1989). This examine confirmed that, when overexpressed, a GPCR can develop into reworking.
Gutkind, J. S., Novotny, E. A., Brann, M. R. & Robbins, okay. C. Muscarinic acetylcholine receptor subtypes as agonist-based oncogenes. Proc. Natl Acad. Sci. u . s . a . 88, 4703-4707 (1991). This work confirmed the remodeling capabilities of usual GPCRs coupled to the Gα q family unit of heterotrimeric G proteins when stimulated via the unrestricted availability of their ligands.
Allen, L. F., Lefkowitz, R. J., Caron, M. G. & Cotecchia, S. G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc. Natl Acad. Sci. us of a 88, 11354–11358 (1991). This look at showed that constitutively active mutations can render GPCRs remodeling.
Coughlin, S. R. Thrombin signalling and protease-activated receptors. Nature 407, 258–264 (2000).
Even-Ram, S. et al. Thrombin receptor overexpression in malignant and physiological invasion techniques. Nature Med. 4, 909–914 (1998). This study showed that the overexpression of thrombin receptors contributes to the acquisition of a metastatic phenotype.
Liu, Y. et al. Expression of protease-activated receptor 1 in oral squamous mobilephone carcinoma. cancer Lett. 169, 173–one hundred eighty (2001).
Daaka, Y. G proteins in cancer: the prostate cancer paradigm. Sci. STKE 2004, re2 (2004).
Lee, Z. et al. Lysophosphatidic acid is an incredible regulator of growth-regulated oncogene alpha in ovarian cancer. cancer Res. 66, 2740–2748 (2006).
Cuttitta, F. et al. Autocrine growth factors in human small phone lung cancer. cancer Surv. four, 707–727 (1985).
Heasley, L. E. Autocrine and paracrine signaling through neuropeptide receptors in human cancer. Oncogene 20, 1563–1569 (2001).
Nelson, J. B. et al. Identification of endothelin-1 within the pathophysiology of metastatic adenocarcinoma of the prostate. Nature Med. 1, 944–949 (1995).
Taub, J. S., Guo, R., Leeb-Lundberg, L. M., Madden, J. F. & Daaka, Y. Bradykinin receptor subtype 1 expression and function in prostate cancer. melanoma Res. sixty three, 2037–2041 (2003).
Ariazi, E. A., Ariazi, J. L., Cordera, F. & Jordan, V. C. Estrogen receptors as therapeutic aims in breast melanoma. Curr. appropriate. Med. Chem. 6, 181–202 (2006).
Feldman, B. J. & Feldman, D. The building of androgen-impartial prostate cancer. Nature Rev. cancer 1, 34–45 (2001).
McDonnell, D. P. & Norris, J. D. Connections and regulation of the human estrogen receptor. Science 296, 1642–1644 (2002).
Filardo, E. J., Quinn, J. A., Bland, okay. I. & Frackelton, A. R. Jr. Estrogen-brought about activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and happens by the use of trans-activation of the epidermal boom element receptor through free up of HB-EGF. Mol. Endocrinol. 14, 1649–1660 (2000).
Carmeci, C., Thompson, D. A., Ring, H. Z., Francke, U. & Weigel, R. J. Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily linked to estrogen receptor expression in breast melanoma. Genomics forty five, 607–617 (1997). the use of differential cDNA hybrid screening, GRP30, which become recognized as a seven transmembrane area receptor, become discovered to be overexpressed in oestrogen receptor-high quality breast carcinoma mobilephone traces. This work supplied the groundwork for future GPR30 reports.
Revankar, C. M., Cimino, D. F., Sklar, L. A., Arterburn, J. B. & Prossnitz, E. R. A transmembrane intracellular estrogen receptor mediates swift phone signaling. Science 307, 1625–1630 (2005).
Thomas, P., Pang, Y., Filardo, E. J. & Dong, J. identification of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146, 624–632 (2005). This analyze identified GRP30 as an oestrogen-activated GPCR.
Kasbohm, E. A. et al. Androgen receptor activation through G(s) signaling in prostate melanoma cells. J. Biol. Chem. 280, 11583–11589 (2005).
Muller, J. M. et al. FHL2, a novel tissue-certain coactivator of the androgen receptor. EMBO J. 19, 359–369 (2000).
Metzger, E., Muller, J. M., Ferrari, S., Buettner, R. & Schule, R. A novel inducible transactivation domain within the androgen receptor: implications for PRK in prostate cancer. EMBO J. 22, 270–280 (2003).
Brown, J. R. & DuBois, R. N. COX-2: a molecular target for colorectal melanoma prevention. J. Clin. Oncol. 23, 2840–2855 (2005).
Gupta, R. A. & Dubois, R. N. Colorectal melanoma prevention and treatment via inhibition of cyclooxygenase-2. Nature Rev. melanoma 1, eleven–21 (2001).
Hull, M. A., Ko, S. C. & Hawcroft, G. Prostaglandin EP receptors: targets for remedy and prevention of colorectal cancer? Mol. melanoma Ther. three, 1031–1039 (2004).
Hansen-Petrik, M. B. et al. Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-caused regression in Apc(Min/+) mice. melanoma Res. 62, 403–408 (2002).
Sonoshita, M. et al. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nature Med. 7, 1048–1051 (2001). This seminal work offered an immediate link between a GPCR, EP2 and colon melanoma development in experimental animal models.
Vogelstein, B. & Kinzler, ok. W. cancer genes and the pathways they handle. Nature Med. 10, 789–799 (2004).
Kikuchi, A. Tumor formation by using genetic mutations in the accessories of the Wnt signaling pathway. melanoma Sci. 94, 225–229 (2003).
Castellone, M. D., Teramoto, H., Williams, B. O., Druey, k. M. & Gutkind, J. S. Prostaglandin E2 promotes colon cancer mobilephone increase via a Gs-axin-beta-catenin signaling axis. Science 310, 1504–1510 (2005).
Shao, J., Jung, C., Liu, C. & Sheng, H. Prostaglandin E2 Stimulates the β-catenin/T telephone component-based transcription in colon melanoma. J. Biol. Chem. 280, 26565–26572 (2005).
Holla, V. R., Mann, J. R., Shi, Q. & DuBois, R. N. Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer. J. Biol. Chem. 281, 2676–2682 (2006).
He, T. C., Chan, T. A., Vogelstein, B. & Kinzler, k. W. PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs. cellphone 99, 335–345 (1999).
Kim, T. H., Xiong, H., Zhang, Z. & Ren, B. β-Catenin activates the increase aspect endothelin-1 in colon melanoma cells. Oncogene 24, 597–604 (2005).
Mazhar, D., Ang, R. & Waxman, J. COX inhibitors and breast cancer. Br. J. cancer 94, 346–350 (2006).
Liu, C. H. et al. Overexpression of cyclooxygenase-2 is enough to set off tumorigenesis in transgenic mice. J. Biol. Chem. 276, 18563–18569 (2001).
Chang, S. H., Ai, Y., Breyer, R. M., Lane, T. F. & Hla, T. The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia. melanoma Res. sixty five, 4496–4499 (2005).
Hida, T. et al. multiplied expression of cyclooxygenase 2 happens generally in human lung cancers, mainly in adenocarcinomas. cancer Res. 58, 3761–3764 (1998).
Lin, D. T., Subbaramaiah, okay., Shah, J. P., Dannenberg, A. J. & Boyle, J. O. Cyclooxygenase-2: a novel molecular target for the prevention and treatment of head and neck melanoma. Head Neck 24, 792–799 (2002).
Bresalier, R. S. et al. Cardiovascular events linked to rofecoxib in a colorectal adenoma chemoprevention trial. N. Engl. J. Med. 352, 1092–1102 (2005).
Chin, L. The genetics of malignant melanoma: training from mouse and man. Nature Rev. cancer 3, 559–570 (2003).
Rees, J. L. Genetics of hair and dermis color. Annu. Rev. Genet. 37, sixty seven–90 (2003).
Palmer, J. S. et al. Melanocortin-1 receptor polymorphisms and possibility of melanoma: is the affiliation defined completely via pigmentation phenotype? Am. J. Hum. Genet. 66, 176–186 (2000).
Rodien, P., Ho, S. C., Vlaeminck, V., Vassart, G. & Costagliola, S. Activating mutations of TSH receptor. Ann. Endocrinol. (Paris) sixty four, 12–sixteen (2003).
Dhanasekaran, N., Heasley, L. E. & Johnson, G. L. G protein-coupled receptor techniques thinking in mobile increase and oncogenesis. Endocr. Rev. sixteen, 259–270 (1995).
Vallar, L., Spada, A. & Giannattasio, G. Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature 330, 566–568 (1987). This study provided proof that the altered exercise of a heterotrimeric G protein contributes to tumorigenesis.
Landis, C. A. et al. GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340, 692–696 (1989). This seminal manuscript supplied a causal link between the mutational activation of a G protein and human tumours.
Lyons, J. et al. Two G protein oncogenes in human endocrine tumors. Science 249, 655–659 (1990).
Parma, J. et al. Somatic mutations within the thyrotropin receptor gene trigger hyperfunctioning thyroid adenomas. Nature 365, 649–651 (1993). this is the primary description of a mutant GPCR concerned in tumorigenesis.
Lum, L. & Beachy, P. A. The Hedgehog response network: sensors, switches, and routers. Science 304, 1755–1759 (2004).
Ruiz i Altaba, A., Sanchez, P. & Dahmane, N. Gli and hedgehog in melanoma: tumours, embryos and stem cells. Nature Rev. cancer 2, 361–372 (2002).
Chen, W. et al. activity-based internalization of smoothened mediated through β-arrestin 2 and GRK2. Science 306, 2257–2260 (2004).
Kasai, ok. et al. The G12 household of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling. Genes Cells 9, 49–58 (2004).
Riobo, N. A., Saucy, B., Dilizio, C. & Manning, D. R. Activation of heterotrimeric G proteins with the aid of Smoothened. Proc. Natl Acad. Sci. u . s . a . 103, 12607–12612 (2006).
Behrens, J. & Lustig, B. The Wnt connection to tumorigenesis. Int. J. Dev. Biol. 48, 477–487 (2004).
Nusse, R. Wnt signaling in disease and in building. mobile Res. 15, 28–32 (2005).
Moon, R. T., Kohn, A. D., De Ferrari, G. V. & Kaykas, A. WNT and β-catenin signalling: illnesses and healing procedures. Nature Rev. Genet. 5, 691–701 (2004).
Liu, T., Liu, X., Wang, H., Moon, R. T. & Malbon, C. C. Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells by the use of pathways that require Gαq and Gαo characteristic. J. Biol. Chem. 274, 33539–33544 (1999).
Malbon, C. C. Frizzleds: new members of the superfamily of G-protein-coupled receptors. front. Biosci. 9, 1048–1058 (2004).
Liu, X., Rubin, J. S. & Kimmel, A. R. speedy, Wnt-triggered alterations in GSK3β associations that alter beta-catenin stabilization are mediated by means of Galpha proteins. Curr. Biol. 15, 1989–1997 (2005). This work, using small interfering RNA in mammalian cells, confirmed that the Gα o subunit interacts with Frizzled and contributes to Wnt-mediated disruption of the Axin–GSK3β complex.
Chambers, A. F., Groom, A. C. & MacDonald, I. C. Dissemination and increase of melanoma cells in metastatic sites. Nature Rev. cancer 2, 563–572 (2002).
Balkwill, F. melanoma and the chemokine community. Nature Rev. melanoma four, 540–550 (2004).
Muller, A. et al. Involvement of chemokine receptors in breast melanoma metastasis. Nature 410, 50–56 (2001). A seminal paper which illustrated that CXCR4 and CCR7 are tremendously expressed in breast cancer cells, thereby explaining why organs that unlock their ligands, SDF1 and CCL21, respectively, function accepted websites for breast cancer phone metastasis.
Epstein, R. J. The CXCL12-CXCR4 chemotactic pathway as a goal of adjuvant breast cancer treatments. Nature Rev. melanoma 4, 901–909 (2004).
Li, Y. M. et al. Upregulation of CXCR4 is elementary for HER2-mediated tumor metastasis. melanoma telephone 6, 459–469 (2004).
Burger, J. A. & Kipps, T. J. CXCR4: a key receptor within the crosstalk between tumor cells and their microenvironment. Blood 107, 1761–1767 (2006).
Semenza, G. L. concentrated on HIF-1 for cancer therapy. Nature Rev. cancer 3, 721–732 (2003).
Staller, P. et al. Chemokine receptor CXCR4 downregulated by means of von Hippel-Lindau tumour suppressor pVHL. Nature 425, 307–311 (2003). This work confirmed that the expression of CXCR4 is below the law of VHL, a protein that negatively regulates HIF.
Ceradini, D. J. et al. Progenitor telephone trafficking is regulated by means of hypoxic gradients via HIF-1 induction of SDF-1. Nature Med. 10, 858–864 (2004).
Zagzag, D. et al. Stromal telephone-derived factor-1α and CXCR4 expression in hemangioblastoma and clear mobile-renal telephone carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. cancer Res. 65, 6178–6188 (2005).
Driessens, M. H., van Rijthoven, E. A., La Riviere, G. & Roos, E. Expression of pertussis toxin adenosine diphosphate-ribosyltransferase in a T-mobile hybridoma reduces metastatic potential. Blood 88, 3116–3123 (1996).
Booden, M. A., Eckert, L. B., Der, C. J. & Trejo, J. Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma mobilephone invasion. Mol. mobile Biol. 24, 1990–1999 (2004).
Asanuma, okay. et al. Thrombin inhibitor, argatroban, prevents tumor mobile migration and bone metastasis. Oncology sixty seven, 166–173 (2004).
Sternlicht, M. D. & Werb, Z. How matrix metalloproteinases adjust cellphone habits. Annu. Rev. telephone Dev. Biol. 17, 463–516 (2001).
Hiratsuka, S., Watanabe, A., Aburatani, H. & Maru, Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nature cell Biol. eight, 1369–1375 (2006).
Rollins, B. J. Inflammatory chemokines in cancer growth and development. Eur. J. cancer 42, 760–767 (2006).
Lee, J. H. et al. KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J. Natl melanoma Inst. 88, 1731–1737 (1996). This turned into the primary illustration that KISS1, already a popular metastasis suppressor, binds to the orphan GPCR, GPR54, and suppresses metastasis. KISS1 is the only GPCR ligand that has been discovered to be a metastasis suppressor up to now.
Steeg, P. S. Metastasis suppressors alter the signal transduction of melanoma cells. Nature Rev. melanoma three, 55–sixty three (2003).
Ohtaki, T. et al. Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 411, 613–617 (2001).
Navenot, J. M., Wang, Z., Chopin, M., Fujii, N. & Peiper, S. C. Kisspeptin-10-brought on signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a possible mechanism for the metastasis suppressor pastime of kisspeptins. cancer Res. 65, 10450–10456 (2005).
Richard, D. E., Vouret-Craviari, V. & Pouyssegur, J. Angiogenesis and G-protein-coupled receptors: signals that bridge the gap. Oncogene 20, 1556–1562 (2001).
Tsopanoglou, N. E. & Maragoudakis, M. E. position of thrombin in angiogenesis and tumor development. Semin. Thromb. Hemost. 30, 63–69 (2004).
Fernandez, P. M., Patierno, S. R. & Rickles, F. R. Tissue ingredient and fibrin in tumor angiogenesis. Semin. Thromb. Hemost. 30, 31–44 (2004).
Strieter, R. M. et al. cancer CXC chemokine networks and tumour angiogenesis. Eur. J. cancer forty two, 768–778 (2006).
Nor, J. E. et al. Up-law of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and hurries up tumor increase. cancer Res. 61, 2183–2188 (2001).
Schruefer, R., Lutze, N., Schymeinsky, J. & Walzog, B. Human neutrophils promote angiogenesis by a paracrine feedforward mechanism involving endothelial interleukin-eight. Am. J. Physiol. heart Circ. Physiol. 288, H1186–H1192 (2005).
Garkavtsev, I. et al. The candidate tumour suppressor protein ING4 regulates mind tumour boom and angiogenesis. Nature 428, 328–332 (2004). This work recognized ING4 as a candidate tumor suppressor gene that negatively regulates NFκB-mediated transcription. decreased expression of ING4, as is present in gliomas, leads to the activation of NFκB signaling and the consequent upregulation of IL8, a amazing seasoned-angiogenic chemokine thinking in glioma tumour progression.
Iniguez, M. A., Rodriguez, A., Volpert, O. V., Fresno, M. & Redondo, J. M. Cyclooxygenase-2: a therapeutic goal in angiogenesis. trends Mol. Med. 9, 73–seventy eight (2003).
Pold, M. et al. Cyclooxygenase-2-stylish expression of angiogenic CXC chemokines ENA-seventy eight/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cellphone lung cancer. melanoma Res. sixty four, 1853–1860 (2004).
Wang, B., Hendricks, D. T., Wamunyokoli, F. & Parker, M. I. A growth-linked oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal melanoma. cancer Res. sixty six, 3071–3077 (2006).
Pai, R. et al. PGE(2) stimulates VEGF expression in endothelial cells by the use of ERK2/JNK1 signaling pathways. Biochem. Biophys. Res. Commun. 286, 923–928 (2001).
Salcedo, R. & Oppenheim, J. J. function of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation 10, 359–370 (2003).
Lasagni, L. et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial mobile increase brought on by means of IP-10, Mig, and that i-TAC, and acts as functional receptor for platelet element four. J. Exp. Med. 197, 1537–1549 (2003).
Milstien, S. & Spiegel, S. concentrated on sphingosine-1-phosphate: a novel avenue for melanoma therapeutics. cancer telephone 9, 148–150 (2006).
Pitson, S. M. et al. Phosphorylation-stylish translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling. J. Exp. Med. 201, 49–fifty four (2005).
Hla, T. Signaling and biological actions of sphingosine 1-phosphate. Pharmacol. Res. 47, 401–407 (2003).
Visentin, B. et al. Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in cutting back boom, invasion, and angiogenesis in numerous tumor lineages. cancer mobile 9, 225–238 (2006).
Leifert, W. R., Aloia, A. L., Bucco, O., Glatz, R. V. & McMurchie, E. J. G-protein-coupled receptors in drug discovery: nanosizing the usage of mobilephone-free technologies and molecular biology processes. J. Biomol. monitor. 10, 765–779 (2005).
Lee, W. P. et al. The -251T allele of the interleukin-8 promoter is linked to expanded risk of gastric carcinoma that includes diffuse-type histopathology in chinese inhabitants. Clin. melanoma Res. 11, 6431–6441 (2005).
Taguchi, A. et al. Interleukin-8 promoter polymorphism raises the possibility of atrophic gastritis and gastric cancer in Japan. cancer Epidemiol. Biomarkers Prev. 14, 2487–2493 (2005).
Tang, C. M. & Insel, P. A. Genetic edition in G-protein-coupled receptors —penalties for G-protein-coupled receptors as drug pursuits. professional Opin. Ther. targets 9, 1247–1265 (2005).
Smith, C. J., Volkert, W. A. & Hoffman, T. J. Radiolabeled peptide conjugates for focused on of the bombesin receptor superfamily subtypes. Nucl. Med. Biol. 32, 733–740 (2005).
Nagy, A. & Schally, A. V. concentrated on cytotoxic conjugates of somatostatin, luteinizing hormone-releasing hormone and bombesin to cancers expressing their receptors: a 'smarter' chemotherapy. Curr. Pharm. Des. eleven, 1167–1180 (2005).
Xu, L. L. et al. PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate melanoma. melanoma Res. 60, 6568–6572 (2000).
Sodhi, A., Montaner, S. & Gutkind, J. S. Viral hijacking of G-protein-coupled-receptor signalling networks. Nature Rev. Mol. mobile Biol. 5, 998–1012 (2004).
Arvanitakis, L., Geras-Raaka, E., Varma, A., Gershengorn, M. C. & Cesarman, E. Human herpesvirus KSHV encodes a constitutively energetic G-protein- coupled receptor linked to phone proliferation. Nature 385, 347–350. (1997).
Sodhi, A. et al. The TSC2/mTOR pathway drives endothelial phone transformation brought on by way of the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. cancer phone 10, 133–143 (2006).
Stallone, G. et al. Sirolimus for Kaposi's sarcoma in renal-transplant recipients. N. Engl. J. Med. 352, 1317–1323 (2005).
Paulsen, S. J., Rosenkilde, M. M., Eugen-Olsen, J. & Kledal, T. N. Epstein-Barr virus-encoded BILF1 is a constitutively active G protein-coupled receptor. J. Virol. 79, 536–546 (2005).
Rosenkilde, M. M. Virus-encoded chemokine receptors--putative novel antiviral drug targets. Neuropharmacology forty eight, 1–13 (2005).
Maussang, D. et al. Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis. Proc. Natl Acad. Sci. united states 103, 13068–13073 (2006).
Dockrell, D. H. Human herpesvirus 6: molecular biology and scientific facets. J. Med. Microbiol. 52, 5–18 (2003).
Chee, M. S., Satchwell, S. C., Preddie, E., Weston, k. M. & Barrell, B. G. Human cytomegalovirus encodes three G protein-coupled receptor homologues. Nature 344, 774–777 (1990).
Casarosa, P. et al. Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28. J. Biol. Chem. 276, 1133–1137 (2001).
Cobbs, C. S. et al. Human cytomegalovirus infection and expression in human malignant glioma. melanoma Res. 62, 3347–3350 (2002).
Vischer, H. F., Leurs, R. & Smit, M. J. HCMV-encoded G-protein-coupled receptors as constitutively active modulators of cellular signaling networks. tendencies Pharmacol. Sci. 27, 56–sixty three (2006).
Hino, S., Tanji, C., Nakayama, okay. I. & Kikuchi, A. Phosphorylation of β-catenin with the aid of cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination. Mol. telephone Biol. 25, 9063–9072 (2005).
Pai, R. et al. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promotion colon cancer increase and gastrointestinal hypertrophy. Nature Med. 8, 289–293 (2002).
Malbon, C. C. Β-catenin, melanoma, and G proteins: no longer only for frizzleds anymore. Sci. STKE 2005, pe35 (2005).
Shi, X., Gangadharan, B., Brass, L. F., Ruf, W. & Mueller, B. M. Protease-activated receptors (PAR1 and PAR2) make contributions to tumor cellphone motility and metastasis. Mol. melanoma Res. 2, 395–402 (2004).
Tsujii, M., Kawano, S. & DuBois, R. N. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic expertise. Proc. Natl Acad. Sci. u . s . ninety four, 3336–3340 (1997).
Servant, G. et al. Polarization of chemoattractant receptor signaling throughout neutrophil chemotaxis. Science 287, 1037–1040 (2000).
Barber, M. A. & Welch, H. C. PI3K and RAC signalling in leukocyte and cancer telephone migration. Bull. melanoma 93, E44–E52 (2006).
Buhl, A. M., Johnson, N. L., Dhanasekaran, N. & Johnson, G. L. Gα12 and Gα13 stimulate Rho-based stress fiber formation and focal adhesion assembly. J. Biol. Chem. 270, 24631–24634 (1995).
Yin, Y. J. et al. Mammary gland tissue targeted overexpression of human protease-activated receptor 1 displays a novel hyperlink to β-catenin stabilization. cancer Res. 66, 5224–5233 (2006).
Boire, A. et al. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast melanoma cells. cell a hundred and twenty, 303–313 (2005).
Harris, R. E. et al. Breast melanoma and nonsteroidal anti-inflammatory medication: potential effects from the women's fitness Initiative. cancer Res. 63, 6096–60101 (2003).
Darmoul, D., Gratio, V., Devaud, H., Lehy, T. & Laburthe, M. Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cellphone proliferation and motility in human colon cancer cells. Am. J. Pathol. 162, 1503–1513 (2003).
Ondrey, F. G. et al. Constitutive activation of transcription elements NF-κB, AP-1, and NF-IL6 in human head and neck squamous mobile carcinoma phone traces that specific professional-inflammatory and professional-angiogenic cytokines. Mol. Carcinog. 26, 119–129 (1999).
Almofti, A. et al. The clinicopathological significance of the expression of CXCR4 protein in oral squamous telephone carcinoma. Int. J. Oncol. 25, 65–seventy one (2004).
Lango, M. N. et al. Gastrin-releasing peptide receptor-mediated autocrine growth in squamous phone carcinoma of the top and neck. J. Natl cancer Inst. ninety four, 375–383 (2002).
Mahmoud, S. et al. [Psi 13,14] bombesin analogues inhibit boom of small mobile lung cancerin vitro and in vivo. cancer Res. fifty one, 1798–1802 (1991).
Kijima, T. et al. law of mobile proliferation, cytoskeletal characteristic, and signal transduction via CXCR4 and c-equipment in small telephone lung cancer cells. melanoma Res. 62, 6304–6311 (2002).
Harris, R. E., Beebe-Donk, J., Doss, H. & Burr Doss, D. Aspirin, ibuprofen, and other non-steroidal anti-inflammatory medicine in cancer prevention: a essential review of non-selective COX-2 blockade (evaluate). Oncol. Rep. 13, 559–583 (2005).
Keane, M. P., Belperio, J. A., Xue, Y. Y., Burdick, M. D. & Strieter, R. M. Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine mannequin of lung cancer. J. Immunol. 172, 2853–2860 (2004).
Phillips, R. J. et al. Epidermal growth component and hypoxia-precipitated expression of CXC chemokine receptor four on non-small telephone lung melanoma cells is regulated by means of the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible component-1α. J. Biol. Chem. 280, 22473–22481 (2005).
Schuller, H. M., Tithof, P. okay., Williams, M. & Plummer, H., 3rd . The tobacco-certain carcinogen 4-(methylnitrosamino)-1-(three-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated free up of arachidonic acid. cancer Res. 59, 4510–4515 (1999).
Szepeshazi, ok., Schally, A. V., Nagy, A. & Halmos, G. Inhibition of boom of experimental human and hamster pancreatic cancers in vivo by way of a targeted cytotoxic bombesin analog. Pancreas 31, 275–282 (2005).
Hoff, A. O. et al. Calcium-prompted activation of a mutant G-protein-coupled receptor reasons in vitro transformation of NIH/3T3 cells. Neoplasia 1, 485–491 (1999).
Kaltsas, G. A. & Grossman, A. B. Malignant pituitary tumours. Pituitary 1, 69–eighty one (1998).
Uemura, H. et al. Renin-angiotensin equipment is an important aspect in hormone refractory prostate melanoma. Prostate 66, 822–830 (2006).
Hayward, N. okay. Genetics of melanoma predisposition. Oncogene 22, 3053–3062 (2003).
Anisowicz, A., Bardwell, L. & Sager, R. Constitutive overexpression of a boom-regulated gene in transformed chinese hamster and human cells. Proc. Natl Acad. Sci. united states 84, 7188–7192 (1987).
Soufir, N. et al. affiliation between endothelin receptor B nonsynonymous variations and melanoma risk. J. Natl melanoma Inst. 97, 1297–1301 (2005).
Xie, J. et al. Activating Smoothened mutations in sporadic basal-mobile carcinoma. Nature 391, ninety–92 (1998).
Liu, G. et al. Leydig-mobilephone tumors brought about via an activating mutation of the gene encoding the luteinizing hormone receptor. N. Engl. J. Med. 341, 1731–1736 (1999).
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